Organelle Research Group

Our research efforts combine expertise in bioanalytical chemistry, chemical biology, and biomedical engineering. We develop unique methods and instrumentation to characterize the chemical, biochemical, and physiological properties of single biological cells and their subcellular components (organelles). These resources enable single cell and subcellular studies that are essential to investigate biological complexity, which presently sets limitations to the research carried out in the biomedical and biotechnological fields.

Within these fields we strive to help answers key questions related to the aging process, diabetes and obesity and neurodegeneration as we apply our developments to biological models including mammalian cell cultures, murine and human skeletal muscle, and Caenorhabditis elegans.

Latest Publication

Metallointercalators-DNA Tetrahedron Supramolecular Self-Assemblies with Increased Serum Stability

M. Andrey Joaqui-Joaqui, Zoe Maxwell, Mandapati V. Ramakrishnam Raju, Min Jiang, Kriti Srivastava, Fangwei Shao, Edgar A. Arriaga, and Valérie C. Pierre*

(2022) ACS Nano



Yukino Nakamura received the CSE Engagement Award

This event, presented by the College of Science and Engineering (CSE), highlighted the many DEI-focused student contributions in the areas of student advocacy, volunteer work, and engagement that have a positive impact on CSE, the University, and the Twin Cities communities through DEI initiatives.


Special Dinner Here!!

Thanks all for joining this special dinner! The current group members and alumni came have the greatest talk.


New Group Website is Published

We now have a new group website where our research identity is showing up!


Yukino Pesents Successfully at SURE Expo

Yukino presented her research poster at SURE Expo that took place on August 5th, 2021. The title of her talk was “Optimization of etoposide treatment in mouse embryonic fibroblast (MEF) cells for development of a cellular senescence model”. Congratulations, Yukino!


Zoe Presents at Great Lakes Regional American Chemical Society Meeting

Zoe presented her research at the 2021 GLRM ACS meeting that took place virtually on June 6 - 9, 2021. The title of her talk was “Single-cell Analysis of Prenylation in Mammalian Cells via Mass Cytometry”. Congratulations on a great talk, Zoe!

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Funding Sources